
Series: In Death #21
Published by Berkley Books on January 31, 2006
Pages: 347
Goodreads

FINAL DECISION: A standout entry in the In Death series that tackles complex ethical questions while delivering a compelling mystery. This is one of my favorites. The exploration of medical ethics and what makes us human elevates this beyond a standard procedural into something more thought-provoking. The relationship between Eve and Roarke shines here as well.
THE STORY: When renowned physician and geneticist Dr. Wilfred B. Icove is found murdered in his office, Lieutenant Eve Dallas investigates his seemingly perfect life and reputation. As Eve digs deeper, she uncovers disturbing secrets about the doctor’s work that lead her into a complex web of medical ethics violations, genetic manipulation, and a scientific conspiracy.
OPINION: ORIGIN IN DEATH stands out for its gripping mystery and the thought-provoking ethical questions it raises. The case is one of the most compelling in the series, delving into medical ethics, genetic engineering, and the definition of personhood. These themes add depth and urgency to what could have been a standard murder investigation.
Eve’s takedown of the Icove legacy is especially satisfying. Her determination to uncover the truth—no matter how unsettling—shows her at the top of her game, both as a detective and as a moral force. The case pushes her to think beyond crime-solving and confront uncomfortable realities.
The relationships in the book also add to its strength. Eve and Roarke continue to grow together, with their different views on the case adding tension and insight. Their dynamic blends emotional connection with sharp dialogue and mutual respect.
The supporting cast contributes meaningfully, too. From Peabody to Mira, each character brings a unique perspective that helps drive the investigation forward. The sense of teamwork is strong and well-developed.
A welcome touch of levity comes with the arrival of Roarke’s Irish relatives, whose warmth and humor bring balance to a story heavy with sci-fi themes and ethical complexity. Their presence adds heart to the book and reminds us of the human connections that ground even the most high-concept cases.
What sets this book apart is how it uses science fiction to explore real-world ethical dilemmas without losing focus on character. It’s smart, engaging, and emotionally grounded—one of the best in the In Death series.
WORTH MENTIONING: There is some conflict between Eve and Mira, which adds depth to their relationship as it is developing through the series.
CONNECTED BOOKS: ORIGIN IN DEATH is the 21st book in the In Death series. While the mystery in this book is standalone, there are continuing and overarching storylines (especially regarding character relationships and development) that continue from book to book. I recommend reading the series in order, although it is not strictly necessary.
STAR RATING: I give this book 5 stars.